GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs965469 | 1 | rs6051764 | chr20:3321807 | ITPA | chr20:3190056-3204504:+ | 0.21 | 5.13 | 4.22E-7 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6051779 | chr20:3333449 | ITPA | chr20:3190056-3204504:+ | -0.23 | -5.77 | 1.41E-8 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6051790 | chr20:3342994 | ITPA | chr20:3190056-3204504:+ | -0.24 | -5.89 | 7.16E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6051792 | chr20:3343519 | ITPA | chr20:3190056-3204504:+ | -0.24 | -5.87 | 8.09E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6051806 | chr20:3350319 | ITPA | chr20:3190056-3204504:+ | -0.25 | -6.03 | 3.35E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6051807 | chr20:3350485 | ITPA | chr20:3190056-3204504:+ | -0.25 | -6.02 | 3.4E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6051808 | chr20:3350697 | ITPA | chr20:3190056-3204504:+ | -0.24 | -5.79 | 1.28E-8 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6051809 | chr20:3352551 | ITPA | chr20:3190056-3204504:+ | -0.24 | -5.88 | 7.62E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6051810 | chr20:3355384 | ITPA | chr20:3190056-3204504:+ | -0.24 | -5.92 | 6.32E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6051827 | chr20:3372007 | ITPA | chr20:3190056-3204504:+ | -0.24 | -5.96 | 4.9E-9 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6051831 | chr20:3373712 | ITPA | chr20:3190056-3204504:+ | 0.24 | 5.8 | 1.21E-8 | IFN-related cytopenia |
| THCA | cis | rs965469 | 1 | rs6051838 | chr20:3389012 | ITPA | chr20:3190056-3204504:+ | -0.23 | -5.85 | 9.18E-9 | IFN-related cytopenia |
| THCA | cis | rs73086581 | 1 | rs6052196 | chr20:3945824 | MAVS | chr20:3827449-3856761:+ | -0.23 | -3.56 | 0.000403 | Response to antidepressants in depression |
| THCA | cis | rs73086581 | 1 | rs6052209 | chr20:3961747 | MAVS | chr20:3827449-3856761:+ | -0.23 | -3.56 | 0.000403 | Response to antidepressants in depression |
| THCA | cis | rs73086581 | 1 | rs6052217 | chr20:3970211 | MAVS | chr20:3827449-3856761:+ | -0.23 | -3.56 | 0.000414 | Response to antidepressants in depression |